New Study Affirms Medical Uses For Marijuana

[Restorium2]

New study affirms medical uses for marijuana

Staff ReportsPublished:  January 13, 2017, 7:56 am

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(WISH) – Jane King at the Nasdaq is reporting a U.S. appeals court on Thursday said Eli Lilly and Company may block Teva Pharmaceutical Industries LTD from selling a generic equivalent of its top-selling lung cancer drug Alimt, and a new large study affirms the medical uses for marijuana.

This has been a closely watched patent case. It means Teva can’t produce any generic versions of Alimta.

Lilly said the patent gives it the right to block U.S. sales of generic Alimta until May 2022.

It has warned that the loss of this right could have significantly harmed its financial results this year.

In other business headlines, a new large study affirms the medical uses for marijuana. The study is 400 pages.

It was released by the National Academies of Science, Engineering, and Medicine.

It is a comprehensive study of current scientific knowledge of medical cannabis and it found that it can effectively treat some patients of chronic pain.

It was found to be particularly effective in treating multiple sclerosis and reduces the nausea associated with chemotherapy treatments.

Edited January 13, 2017 by Restorium2

[Restorium2]

The good, bad, and unknown about marijuana's health effects

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Last Updated Jan 12, 2017 7:32 PM EST

NEW YORK -- It can almost certainly ease chronic pain and might help some people sleep, but it’s also likely to raise the risk of getting schizophrenia and might trigger heart attacks.

Those are among the conclusions about marijuana reached by a federal advisory panel in a report released Thursday.

Play VIDEO

Landmark report released on marijuana's health benefits, hazards

The experts also called for a national effort to learn more about marijuana and its chemical cousins, including similarly acting compounds called cannabinoids.

The current lack of scientific information “poses a public health risk,” said the report, released by the National Academies of Sciences, Engineering and Medicine. Patients, health care professionals and policy makers need more evidence to make sound decisions, it said.

It was hard for the researchers to make definitive conclusions, said CBS News’ Chief Medical Correspondent Dr. Jon LaPook, because a lot of the literature is based off of self-reporting -- and there was no standardization. For example, there are over 100 different cannabinoid chemcials in cannabis, and many different forms of using it. 

Several factors have limited research. While the federal government has approved some medicines containing ingredients found in marijuana, it still classifies marijuana as illegal and imposes restrictions on research. So scientists have to jump through bureaucratic hoops that some find daunting, the report said.

Play VIDEO

Big Pot: The commercial takeover

A federal focus on paying for studies of potential harms has also impeded research into possible health benefits, the report said. The range of marijuana products available for study has also been restricted, although the government is expanding the number of approved suppliers.

Twenty-eight states and the District of Columbia have legalized marijuana for a variety of medical uses, and eight of those states plus the district have also legalized it for recreational use.

The report lists nearly 100 conclusions about marijuana and its similarly acting chemical cousins, drawing on studies published since 1999.

It found strong evidence, for example, that marijuana can treat chronic pain in adults and that similar compounds ease nausea from chemotherapy, with varying degrees of evidence for treating muscle stiffness and spasms in multiple sclerosis.

Limited evidence says marijuana or the other compounds can boost appetite in people with HIV or AIDS, and ease symptoms of post-traumatic stress disorder, the report concluded. But it said there’s not enough research to say whether they’re effective for treating cancers, irritable bowel syndrome, epilepsy, or certain symptoms of Parkinson’s disease, or helping people beat addictions.

There may be more evidence soon: a study in Colorado is investigating the use ofmarijuana to treat PTSD.

Turning to potential harms, the committee concluded:

- Strong evidence links marijuana use to the risk of developing schizophrenia and other causes of psychosis, with the highest risk among the most frequent users.

- Some evidence suggests a small increased risk for developing depressive disorders, but there’s no evidence either way on whether it affects the course or symptoms of such disorders, or the risk of developing post-traumatic stress disorder.

- There’s strong evidence that using marijuana increases the risk of a traffic accident, but no clear indication that it promotes workplace accidents or injuries, or death from a marijuana overdose.

- There’s only weak evidence for the idea that it hurts school achievement, raises unemployment rates or harms social functioning.

- For pregnant women who smoke pot, there’s strong evidence of reduced birthweight but only weak evidence of any effect on pregnancy complications for the mother, or an infant’s need for admission to intensive care. There’s not enough evidence to show whether it affects the child later, like sudden infant death syndrome or substance use.

- Some evidence suggests there’s no link to lung cancer in marijuana smokers. But there’s no evidence, or insufficient evidence, to support or rebut any link to developing cancers of the prostate, cervix, bladder, or esophagus.

- Substantial evidence links pot smoking to worse respiratory symptoms and more frequent episodes of chronic bronchitis.

- There’s weak evidence that suggests smoking marijuana can trigger a heart attack, especially for people at high risk of heart disease. But there’s no evidence either way on whether chronic use affects a person’s risk of a heart attack.

- Some evidence suggests a link between using marijuana and developing a dependence on or abuse of other substances, including alcohol, tobacco and illicit drugs.

Edited January 13, 2017 by Restorium2

[cristinew]

Its just bad for you  Just Say No  

[Restorium2]

Its just bad for you  Just Say No  

If we only had the choice. Really had the choice, not a fake choice. 

[cristinew]

synthetic  is safe .. Natural is evil...

 

http://zynerba.com/in-development/thc-pro-drug-patch-zyn001/ 

ZYN001 is a  pro-drug of THC that enables effective transdermal delivery via a patch. A Phase 1 study is expected to be initiated in the first half of 2017. ZYN001 is patent-protected through 2031. Learn more about pro-drugs.

http://zynerba.com/in-development/cbd-gel-zyn002/  

 

First and Only Synthetic CBD Formulated as a Permeation-Enhanced Gel Being Developed for Refractory Epilepsy, Osteoarthritis and Fragile X Syndrome

[bax]

why would you use a transdermal gel for delivery of epilepsy medication? thats one of the slowest methods and the worst absorption rate.

 

especially when cbd is tolerated very well orally , not to mention under tongue or even nasal spray.

 

good, remind me not to invest in zynerba.