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t-pain

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  1. Seeking petitioners for new MMMA conditions!

    no, please do ramble. its interesting and reminds me of a question. do you use the cannabis roots at all? i am assuming you would pull them out of the ground , remove dirt, grind into a paste and either mix or dont mix it with something to penetrate skin (olive oil?). but i dont know if the roots have the same powers or maybe alkaloids that would upset skin. more research is needed! hah
  2. ran across this article about historical antedotes to cannabis intoxication / side effects. not sure if useful but here you go for funs. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165946/ Taming THC: cannabis entourage compounds as antidotes to intoxication Various sources highlight the limited therapeutic index of pure THC, when given intravenously (D'Souza et al., 2004) or orally (Favrat et al., 2005), especially in people previously naïve to its effects. Acute overdose incidents involving THC or THC-predominant cannabis usually consist of self-limited panic reactions or toxic psychoses, for which no pharmacological intervention is generally necessary, and supportive counselling (reassurance or ‘talking down’) is sufficient to allow resolution without sequelae. CBD modulates the psychoactivity of THC and reduces its adverse event profile (Russo and Guy, 2006), highlighted by recent results above described. Could it be, however, that other cannabis components offer additional attenuation of the less undesirable effects of THC? History provides some clues. In 10th century Persia, Al-Razi offered a prescription in his Manafi al-agdhiya wa-daf madarri-ha (p. 248), rendered (Lozano, 1993, p. 124; translation EBR) ‘– and to avoid these harms {from ingestion of cannabis seeds or hashish}, one should drink fresh water and ice or eat any acid fruits’. This concept was repeated in various forms by various authorities through the ages, including ibn Sina (ibn Sina (Avicenna), 1294), and Ibn al-Baytar (ibn al-Baytar, 1291), until O'Shaughnessy brought Indian hemp to Britain in 1843 (O'Shaughnessy, 1843). Robert Christison subsequently cited lemon (Figure 3A) as an antidote to acute intoxication in numerous cases (Christison, 1851) and this excerpt regarding morning-after residua (Christison, 1848) (p. 973): Figure 3 Ancient cannabis antidotes. (A) Lemon (Citrus limon). (B) Calamus plant roots (Acorus calamus). (C) Pine nuts (Pinus spp.). (D) Black pepper (Piper nigrum). Next morning there was an ordinary appetite, much torpidity, great defect and shortness of memory, extreme apparent protraction of time, but no peculiarity of articulation or other effect; and these symptoms lasted until 2 P.M., when they ceased entirely in a few minutes after taking lemonade. Literary icons on both sides of the Atlantic espoused similar support for the citrus cure in the 19th century, notably Bayard Taylor after travels in Syria (Taylor, 1855), and Fitzhugh Ludlow after his voluntary experiments with ever higher cannabis extract doses in the USA (Ludlow, 1857). The sentiment was repeated by Calkins (1871), who noted the suggestion of a friend in Tunis that lemon retained the confidence of cure of overdoses by cannabis users in that region. This is supported by the observation that lemon juice, which normally contains small terpenoid titres, is traditionally enhanced in North Africa by the inclusion in drinks of the limonene-rich rind, as evidenced by the recipe for Agua Limón from modern Morocco (Morse and Mamane, 2001). In his comprehensive review of cannabis in the first half of the 20th century, Walton once more supported its prescription (Walton, 1938). Another traditional antidote to cannabis employing Acorus calamus (Figure 3B) is evident from the Ayurvedic tradition of India (Lad, 1990, p. 131): Calamus root is the best antidote for the ill effects of marijuana. . . . if one smokes a pinch of calamus root powder with the marijuana, this herb will completely neutralize the toxic side effects of the drug. This claim has gained credence, not only through force of anecdotal accounts that abound on the Internet, but with formal scientific case reports and scientific analysis (McPartland et al., 2008) documenting clearer thinking and improved memory with the cannabis–calamus combination, and with provision of a scientific rationale: calamus contains beta-asarone, an acetylcholinesterase inhibitor with 10% of the potency of physotigmine (Mukherjee et al., 2007). Interestingly, the cannabis terpenoid, a-pinene, also has been characterized as a potent inhibitor of that enzyme (Miyazawa and Yamafuji, 2005), bolstering the hypothesis of a second antidote to THC contained in cannabis itself. Historical precedents also support pinene in this pharmacological role. In the firstt century, Pliny wrote of cannabis in his Natural History, Book XXIV (Pliny, 1980, p. 164): The gelotophyllis [‘leaves of laughter’ = cannabis] grows in Bactria and along the Borysthenes. If this be taken in myrrh and wine all kinds of phantoms beset the mind, causing laughter which persists until the kernels of pine-nuts are taken with pepper and honey in palm wine. Of the components, palm wine is perhaps the most mysterious. Ethanol does not reduce cannabis intoxication (Mello and Mendelson, 1978). However, ancient wines were stored in clay pots or goatskins, and required preservation, usually with addition of pine tar or terebinth resin (from Pistacia spp.; McGovern et al., 2009). Pine tar is rich in pinene, as is terebinth resin (from Pistacia terebinthus; Tsokou et al., 2007), while the latter also contains limonene (Duru et al., 2003). Likewise, the pine nuts (Figure 3C) prescribed by Pliny the Elder harbour pinene, along with additional limonene (Salvadeo et al., 2007). Al-Ukbari also suggested pistachio nuts as a cannabis antidote in the 13th century (Lozano, 1993), and the ripe fruits of Pistacia terebinthus similarly contain pinene (Couladis et al., 2003). The black pepper (Figure 3D), might offer the mental clarity afforded by pinene, sedation via myrcene and helpful contributions by ß-caryophyllene. The historical suggestions for cannabis antidotes are thus supported by modern scientific rationales for the claims, and if proven experimentally would provide additional evidence of synergy (Berenbaum, 1989; Wagner and Ulrich-Merzenich, 2009).
  3. Seeking petitioners for new MMMA conditions!

    unfortunately the panel (and various department heads) have indicated a few times that it would absolutely not approve of mental conditions. we'll see how the anxiety petition goes.
  4. Seeking petitioners for new MMMA conditions!

    right, theres a few pieces of research i see. not much but anything is better than nothing. https://www.ncbi.nlm.nih.gov/pubmed/27164964 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757311/ there are more. i'll write up a petition. basically, all you have to do is print, fill out and sign page 3 of the petition form http://www.michigan.gov/documents/lara/lara_BHCS_MMMP_ReviewPanelInstructions_4-1-15_485883_7.pdf and then attach it to the petition i will write (along with the research papers i am getting). then submit it to LARA at the address provided in the above pdf. or you can send the signed form to us and we'll submit it with Michael as a second contact. would you want to do that , 420mama ?
  5. Seeking petitioners for new MMMA conditions!

    glad to hear it 420mama. arthritis is already a petition. hopefully it will cover all kinds of arthritis. i will look for studies on psoriasis + marijuana right now. the petitions will be submitted very shortly.
  6. BOB! hey bob! i got an idea tell the grower group to ban all pesticides and go for the clean system. basically use diatomacceous earth instead of pesticides. stick to worm castings and rock dust and compost tea , ignore synthetic nutrients!
  7. https://www.legislature.mi.gov/documents/2017-2018/billintroduced/House/htm/2017-HIB-4965.htm call and visit in person with gary glenn and tell him your opinion on this bill of his! Contact PHONE: 517-373-1791 EMAIL: GaryGlenn@house.mi.gov HOUSE BILL No. 4965 September 14, 2017, Introduced by Rep. Glenn and referred to the Committee on Law and Justice. A bill to amend 1971 PA 140, entitled "Glenn Steil state revenue sharing act of 1971," (MCL 141.901 to 141.921) by adding section 17b. THE PEOPLE OF THE STATE OF MICHIGAN ENACT: Sec. 17b. The state treasurer shall withhold all or any part of any payment that a city, village, township, or county is eligible to receive under this act if the city, village, township, or county adopts a medical marihuana ordinance. obviously this bill is DOA , since it also defunds cities and entire counties! that enact ordinances banning medical marijuana. but it shows you just how small minded this gary glenn person really is. literally de-funding your city if your city enacts an ordinance to allow a dispensary for sick people. time to recall this loser gary glenn, midland and bay city. DISTRICT Rep. Gary Glenn was first elected to the Michigan House in November 2014. He represents the 98th District, which includes portions of Bay and Midland counties. Within Bay County, Glenn represents the cities of Auburn and Pinconning, Linwood, and the townships of Beaver, Fraser, Garfield, Gibson, Mount Forest, Pinconning, and Williams. In Midland County, the district includes the city of Midland, the village of Sanford, and the townships of Midland, Homer, Jerome, Larkin, Lee and Lincoln. tell him on facebook too, https://www.facebook.com/RepresentativeGaryGlenn/
  8. Dirty Rat Rippers In Caro

    and dont set booby traps either. do secure your grow with fences though. strange they didnt get him on home invasion. must have been outdoor grow.
  9. Seeking petitioners for new MMMA conditions!

    Autism is one of the petitions to be resubmitted, yes. I wonder when they will be submitted?
  10. Cannabis Growers Ignore California Law

    wtf? http://www.sandiegouniontribune.com/business/energy-green/sd-fi-cannabis-deadline-20170626-story.html Regulations for production and sale of adult-use cannabis are due at the beginning of 2018, and the scope of the rollout is huge — including cultivation, manufacturing, testing, distribution and sales. the program hasnt even started yet. people are waiting for the rules and forms to register in 2018. what a crap article.
  11. Here are the other two previous IOM reports. pdf can be downloaded just click "continue as guest"... 1999 Institute of Medicine report Marijuana and medicine assessing thescience basehttps://www.nap.edu/catalog/6376/marijuana-and-medicine-assessing-the-science-base1982 Institute of Medicine report marijuana and healthhttps://www.nap.edu/catalog/18942/marijuana-and-health
  12. Almost had electrical fire

    I had a 220 intermatic timer melt on me. i think it arc'd due to bad/lose connection on the plug, possibly because of corrosion on the hottub plug. good reason to follow the recommended rules of grow rooms. glad you didnt lose anything important! do we have a list of tips? theres some in some grow books. count your amps. do not use any wires with cuts or nicks in them. touch wires after they are on for a time to see if they get hot. keep wires and cables tied and above the ground if possible. do not run extension cords over carpet. keep fire extinguishers up to date and handy. check smoke detectors on a regular basis.
  13. Full MMFLA Board meeting Video

    i doubt licenses will be transferable . that would cut into the application fees.
  14. Full MMFLA Board meeting Video

    in my opinion, same as all other board members (well not the qualifying conditions board) in this corrupt state. get bribes from stakeholders, delay implementation as long as possible. get bribes from pharma/prisons for delaying/restricting. give licenses to friends and family (e.g. make more money). give license to people who will then bribe with a job after the appointment time is up-- just more money. i dont think caring about patients is on the list. the list of reasons people are on the board is: money money money money money money and money and power.
  15. The 1999 IOM report was cited as evidence used to create the MMMA. now some 18 years later, the new report has been released! https://www.nap.edu/catalog/24625/the-health-effects-of-cannabis-and-cannabinoids-the-current-state download pdf easier from here https://www.ncbi.nlm.nih.gov/books/NBK423845/ Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agenda—outlining gaps in current knowledge and opportunities for providing additional insight into these issues—that summarizes and prioritizes pressing research needs.
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