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t-pain

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  1. Only thing you have to watch out for is dose. If you see a large bottle of cbd oil in the store, it can be a lot of filler and only a few hundred mg of CBD. you need something at least 200mg 2-3x day of CBD to even have a therapeutic effect. CBD + THC can take less of because they work in tandem. https://www.ncbi.nlm.nih.gov/pubmed/30402932 There are hundreds of compounds found in the marijuana plant, each contributing differently to the antiepileptic and psychiatric effects. Cannabidiol (CBD) has the most evidence of antiepileptic efficacy and does not have the psychoactive effects of ?9 -tetrahydrocannabinol. CBD does not act via cannabinoid receptors and its antiepileptic mechanism of action is unknown. Despite considerable community interest in the use of CBD for paediatric epilepsy, there has been little evidence for its use apart from anecdotal reports, until the last year. Three randomized, placebo-controlled, double-blind trials in Dravet syndrome and Lennox-Gastaut syndrome found that CBD produced a 38% to 41% median reduction in all seizures compared to 13% to 19% on placebo. Similarly, CBD resulted in a 39% to 46% responder rate (50% convulsive or drop-seizure reduction) compared to 14% to 27% on placebo. CBD was well tolerated; however, sedation, diarrhoea, and decreased appetite were frequent. CBD shows similar efficacy to established antiepileptic drugs. WHAT THIS PAPER ADDS: Cannabidiol (CBD) shows similar efficacy in the severe paediatric epilepsies to other antiepileptic drugs. Careful down-titration of benzodiazepines is essential to minimize sedation with adjunctive CBD.
  2. t-pain

    Questions

    Hope you find something Codger. Maybe you could try starting an adult legalization club at your local library to educate adults and connect them to each other for the gifting of marijuana (which takes place in private, not at the library). the club would just be for adults to talk, not to smoke/trade etc. LEGALIZATION CLUB
  3. Quickest legal way to make money? Open a hydro grow supply store in an area that needs it. Or in a municipality that has opted out / banned dispensaries. A city that bans dispensaries means more people will grow in those areas.
  4. t-pain

    Georgia Medical Card

    Visiting qualifying patients are part of the MMMA. Out of state cards are accepted by the MMMA too. Some people do go to Michigan, in winter. possibly for family during Thanksgiving. These people still need medicine. Please be considerate of patients from around the USA.
  5. Came across this tidbit of science, worth repeating. Researchers tested people to see if THC and CBD helped prevent migraines. It did! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968020/ Patterns of medicinal cannabis use, strain analysis, and substitution effect among patients with migraine, headache, arthritis, and chronic pain in a medicinal cannabis cohort There are only two prospective trials containing a control group evaluating the use of cannabinoids in the treatment of headache disorders, specifically chronic migraine, cluster headache, and medication overuse headache [56, 62]. The first of these two prospective trials was a randomized, double-blind, active-controlled crossover trial with treatment refractory medication overuse headache (MOH) with daily analgesic intake for at least 5 years and several failed detoxification attempts. Patients completed a course of either Ibuprofen 400 mg or Nabilone 0.5 mg daily for 8 weeks, had a 1 week washout, then a second 8 weeks of the other medication. Results showed that Nabilone 0.5 mg daily, a synthetic cannabinoid, was superior in reducing daily analgesic intake, pain intensity, level of medication dependence, and improved quality of life in these patients [62]. The second prospective trial evaluated the use of cannabinoids as both a prophylaxis and acute treatment for both chronic migraine and chronic cluster headache [56]. Patients were given one of two compounds containing 19% THC or a combination of 0.4% THC + 9% CBD. In phase 1, dose finding observations to determine effective dosing was performed with a group of 48 chronic migraineurs. It was found that doses less than 100 mg produced no benefit, while an oral dose of 200 mg administered during a migraine attack decreased acute pain intensity by 55%, which was the dose used in phase 2. In phase 2, chronic migraine patients were assigned to 3 months prophylaxis treatment with either 25 mg per day of Amitriptyline or THC + CBD 200 mg per day. Chronic cluster headache patients were assigned to 1 month prophylaxis treatment with either Verapamil 480 mg per day or THC + CBD 200 mg per day. For acute pain attacks, additional dosing of THC + CBD 200 mg was allowed in both groups. In the migraine patients, the THC + CBD 200 mg prophylaxis provided a 40.4% improvement versus 40.1% with Amitriptyline. In the cluster headache patients, the THC + CBD 200 mg prophylaxis gave minimal to no benefit. Additional acute THC + CBD 200 mg dosing decreased pain intensity in migraine patients by 43.5%. This same result was seen in cluster headache patients, but only if they had a history of migraine in childhood. In cluster headache patients without a previous history of childhood migraine, the additional THC-CBD 200 mg abortive treatment provided no benefit as an acute treatment.
  6. t-pain

    Georgia Medical Card

    No, Michigan does not restrict products to low THC, if you have an out of state med card. You may want to call ahead to a specific dispensary to ask if they accept out of state/Georgia cards. I would say they should, but its kind of a strange thing as your state is not really true medical marijuana. However I do not see Georgia in the list that Michigan LARA created. Probably because a "low thc oil" "only" card is not really a medical marijuana card. Does your card look like this? https://www.michigan.gov/documents/lara/Ohio_Patient_ID_Cards_and_Out_of_State_Registration_624599_7.pdf Based on the available data, the following states are currently issuing medical marihuana cards or registration certifications to patients: • Alaska • Arizona • California • Colorado • Connecticut • Delaware • Florida • Hawaii • Illinois • Maine • Maryland • Massachusetts • Minnesota • Montana • Nevada • New Hampshire • New Jersey • New Mexico • New York • Ohio# • Oregon • Pennsylvania • Rhode Island • Vermont • Washington • Washington DC • West Virginia*
  7. As Ethics go, you should probably not have any non-social worker relationship with any of your clients. this is probably in your social worker manual. Which means you could continue to be a caregiver, but get another case worker to take this case.
  8. t-pain

    Robbed

    The profile picture changes are due to people using facebook to login. When they change facebook photo, it changes here too. Very annoying.
  9. Letter to the editor Published 10:50 am EDT, Friday, October 5, 2018 To the editor, Cannabis should be legal and regulated for adults. Proposal 1 would regulate cannabis possession for adults away from kids, cars, and the public, and impose a 10 percent sin tax on cannabis sales plus 6 percent sales tax. It would forbid sales except through state licensed businesses. Licensed shop owners won't get rich. The IRS forbids normal business tax deductions so about 80 percent of profits will go straight into the public treasury. Proposal 1 protects landlords who don't want cannabis on their property, protects employers with workplace drug policies, keeps cannabis away from schools, and provides for drugged driving arrests for abusers. As an attorney I watched many lives ruined due to marijuana law enforcement, but cannabis itself poses no public safety threat. It is not a gateway drug, is not addictive, and is not harmful to humans. Cannabis is as popular as beer. Alcohol prohibition ended 85 years ago, and it is time to end cannabis prohibition. As a Republican and civil libertarian my view is that limited government, based on personal liberty and rule of law, should not try account for tastes. Laws that don't respect people breed people who don't respect laws. Vote "yes" on Proposal 1. Gregory Carl Schmid Saginaw https://www.michigansthumb.com/opinion/article/Attorney-on-pot-It-is-not-a-gateway-drug-13284185.php
  10. t-pain

    Patient Grow Rules

    it is settled law in ter beek v wyoming http://komornlaw.com/mmma-court-case-library/ http://komornlaw.com/wp-content/uploads/2018/05/Ter-Beek-v-Wyoming-S145816.pdf
  11. t-pain

    Proposal 1

    MPP was filming some commercials yesterday with retired police officers and other interested parties. dont know when will air. but soon! get all your friends and family to check if they are still registered to vote before oct 9th.
  12. t-pain

    Patient Grow Rules

    No, patient can grow anywhere they own or lease land/property according to the MMMA. But be sure you secure your grow if outdoors and cannot be visible and must have roof etc. Don't want people stealing plants.
  13. t-pain

    Denied twice over penmanship?

    I have heard LARA doing this in the past, but not recently. You may want to call LARA and ask them why they think they can deny a person for handwriting, also this may be an ADA violation to discriminate against you (you should mention this, write a separate note when you send in your application stating you feel you are being discriminated upon for being disabled).. Seems like an arbitrary reason to reject you. My only suggestion is try having someone else write the application for you and or use the computer to enter most of your information ,then just sign it. LARA will be adding online applications next month which may speed up the process of getting registered, and possibly get rid of the step of handwriting anything.
  14. I missed a video. March 2018 Unfortunately she cannot kick her sugar addiction. The addiction is REAL. Sugar and refined carbs that turn into sugar will literally kill you. I wonder if it was the tumors that tricked her brain into craving sugar? Just a theory. Kristina Marie has died. She gave her brain tumors quite a fight for 5 years after the diagnosis. What a journey this has been.
  15. t-pain

    Michigan Ginseng

    where do you get a large amount of ginseng seeds? i thought they were very expensive last time i bought some.
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