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Found 16 results

  1. Let's Be Blunt with Montel Charles McElroy is the founder of Goldleaf, a science-forward printing company for cannabis growers, patients, and enthusiasts. McElroy is a former volunteer with the Marijuana Policy Project, has a history of supporting veterans education and access to medical marijuana, and several years studying permaculture and organic farming in Ohio and Colorado. McElroy created Goldleaf to benefit the evolving recreational and medical cannabis communities. Goldleaf brings a clear and credible perspective to the cannabis community by pairing compelling design with the latest peer-reviewed research. Goldleaf products are available worldwide and the company also provides custom design services, now adorning select dispensaries and white-label products across the U.S. Formerly COO at Noble Denim & Victor Athletics, a sustainable and ethical clothing manufacturer, McElroy holds a B.S. in Engineering Technology and Management from Ohio University with an MBA track at Miami University in Business Informatics.
  2. Let's Be Blunt with Montel Over two decades as an activist, Andrew DeAngelo worked on a variety of voter initiatives which legalized medical and adult use cannabis in San Francisco, Washington D.C, and the State of California. As a co-founder and advisor to one of the oldest and largest cannabis retailers in the world, Harborside, Andrew has pioneered legal cannabis business processes and provided groundbreaking political engagement and thought leadership to the cannabis community — leading the design and development of gold-standard cannabis retail by innovating many “firsts” for the industry. This includes: introducing CBD medicines to heal severely epileptic children, implementing the first lab-testing program in the history of cannabis dispensing, creating child-resistant packaging for edibles, standardizing inventory tracking, initiating senior outreach, and successfully preventing the federal government from seizing Harborside in forfeiture actions against the company in 2012. Andrew began his political career as an activist while studying for his MFA in acting at the American Conservatory Theatre in San Francisco. He has starred in several films and runs an entertainment production company, DeAngelo Brothers Productions (DAB), with his brother Steve. Andrew is co-founder and Treasurer of the Board for the non-profit Last Prisoner Project (LPP) and a founding Board of Directors member of the California Cannabis Industry Association (CCIA) where he served from 2013 to 2020.
  3. Statement by FDA Commissioner Scott Gottlieb, M.D., on the importance of conducting proper research to prove safe and effective medical uses for the active chemicals in marijuana and its components. Over the past decade, we’ve seen a growing interest in the development of therapies derived from marijuana and its components. Proponents of “medical marijuana” advertised its uses for a wide number of medical conditions, such as cancer, multiple sclerosis, post-traumatic stress disorder and anxiety – just to name a few of the touted conditions. The FDA has been supportive of research in this area for many years. But marijuana is a Schedule I compound with known risks. Research to demonstrate that marijuana or its components could be safe and effective in the treatment of medical disorders should be held to the same standard as other drug compounds. And certainly it should not be held to a lower standard, as some proponents would suggest. The FDA has an active program to assist drug developers who want to investigate marijuana or its components through properly controlled clinical trials, to demonstrate the potential for safe and effective uses. Today, the FDA approved a purified form of the drug cannabidiol (CBD). This is one of more than 80 active chemicals in marijuana. The new product was approved to treat seizures associated with two rare, severe forms of epilepsy in patients two years of age and older. This product approval demonstrates that advancing sound scientific research to investigate ingredients derived from marijuana can lead to important therapies. This new treatment provides new options for patients. This is an important medical advance. But it’s also important to note that this is not an approval of marijuana or all of its components. This is the approval of one specific CBD medication for a specific use. And it was based on well-controlled clinical trials evaluating the use of this compound in the treatment of a specific condition. Moreover, this is a purified form of CBD. It’s being delivered to patients in a reliable dosage form and through a reproducible route of delivery to ensure that patients derive the anticipated benefits. This is how sound medical science is advanced. So today, in addition to celebrating this scientific achievement and the medical advance that it represents for these patients and their families, we should also reflect on the path that made this possible. It’s a path that’s available to other product developers who want to bring forth marijuana-derived products through appropriate drug development programs. That pathway includes a robust clinical development program, along with careful review through the FDA’s drug approval process. This is the most appropriate way to bring these treatments to patients. This process also includes a review of the purity of a new drug and manufacturing controls. Before a high-quality drug can be developed, evaluated, and eventually approved by the FDA; it’s critical that the necessary work is done to identify drugs of potential medical benefit and conduct rigorous scientific research through adequate and well-controlled clinical trials. This is true for all drugs, including ones derived from plant materials, like marijuana. And the FDA remains committed to collaborating with federal and state agencies, researchers and product developers on advancing this type of important and conscientious work. This research process – from early development through preclinical and clinical research – gives us a comprehensive understanding of a new drug. That includes an understanding of whether the new product is safe and effective for treating a particular medical condition, what the proper dosage is and for what populations it is safe and effective, how the new compound could interact with other drugs, or whether the new drug has side effects or other safety concerns. This work also helps product developers identify the appropriate dosage needed to achieve the desired therapeutic effect while minimizing toxicity and risk. Taken in totality, the scientific evidence generated by these studies forms the basis of the FDA’s evaluation of benefit versus risk. And it’s because of this careful, scientific and evidence-based evaluation by the FDA that health care providers can rely on having a quality product that delivers a consistent, uniform dose of an effective medication that is able to deliver a predictable treatment to patients. This is especially important when considering treatment for serious medical conditions that will be utilized in the clinical care of patients who may have any number of health vulnerabilities. The purified form of the drug CBD approved today by the FDA has been shown to meet these rigorous standards. Research on the therapeutic effects of marijuana and its components involves a number of federal agencies in addition to the FDA, including the National Institute on Drug Abuse, part of the National Institutes of Health, and the Drug Enforcement Administration. The FDA has taken several specific steps to support this research. We meet regularly with researchers as they plan and carry out their trials. We have also formed a Botanicals Team that provides scientific expertise on botanical issues for researchers developing drugs derived from plants, such as marijuana. That team published guidance for industry on clinical studies involving botanical drugs, as well as quality controls for lot-to-lot consistency. In recent years, the agency also has recommended to the DEA the approval of several hundred Schedule I research protocol licenses for research on marijuana or its constituent compounds. Additionally, the FDA also works with companies to provide patients access to experimental therapies while clinical trials are ongoing through expanded access provisions. These approaches help protect patients while also allowing for the collection of data necessary to support the FDA approval of safe and effective therapies for use in the broader population. Through this process, hundreds of children were able to get access to investigational CBD products while this product was being studied. Drugs derived from marijuana also are eligible for several programs that are intended to facilitate and expedite development and review of new drugs that address unmet medical needs in the treatment of serious or life-threatening conditions. Much of the work we’ve done to encourage research in this area has led to the approval action we took today. The FDA will continue to support rigorous scientific research on potential medical treatments using marijuana and its components that seek to be developed through the appropriate scientific channels. However, we remain concerned about the proliferation and illegal marketing of unapproved CBD-containing products with unproven medical claims. The promotion and use of these unapproved products may keep some patients from accessing appropriate, recognized therapies to treat serious and even fatal diseases. The FDA has taken recent actions against companies distributing unapproved CBD products. These products have been marketed in a variety of formulations, such as oil drops, capsules, syrups, teas, and topical lotions and creams. These companies have claimed that various CBD products could be used to treat or cure serious diseases such as cancer with no scientific evidence to support such claims. We’ll continue to take action when we see the illegal marketing of CBD-containing products with unproven medical claims. We’re especially concerned when these products are marketed for serious or life threatening diseases, where the illegal promotion of an unproven compound could discourage a patient from seeking other therapies that have proven benefits. Today’s approval demonstrates our commitment to the scientific process and working with product developers to bring marijuana-based products to market. We remain committed to our gold standard for product development and review. Such a process ensures that any new therapies from marijuana and its constituents are safe, effective and manufactured to a high and consistent quality. And most importantly, that these products have been proven safe and effective for patients. The FDA, an agency within the U.S. Department of Health and Human Services, protects the public health by assuring the safety, effectiveness, and security of human and veterinary drugs, vaccines and other biological products for human use, and medical devices. The agency also is responsible for the safety and security of our nation’s food supply, cosmetics, dietary supplements, products that give off electronic radiation, and for regulating tobacco products.
  4. Hello, I’m currently a hobbyist grower and ER nurse. I have been researching extensively on the medical benefits of cannabis. I sincerely believe it will slow or stop the growth of many different cancers. I’m upset that it isn’t encouraged more by doctors or offered by doctors. I want to help. I can help you make RSO or make it for you, help you choose and grow plants, give you grow advice, grow for you. My assistance is free for cancer patients. I live south of Kalamazoo outside of the city. Yes it’s free. I want to help. I’m not rich but I will do whatever I can. Please contact poster via private message private email or other outside links not allowed in open forum . if you want to see some of what I do.
  5. https://www.ncbi.nlm.nih.gov/pubmed/26800377 RESULTS: CBD treatment yielded a significant positive effect on seizure load. Most of the children (66/74, 89%) reported reduction in seizure frequency: 13 (18%) reported 75-100% reduction, 25 (34%) reported 50-75% reduction, 9 (12%) reported 25-50% reduction, and 19 (26%) reported <25% reduction. Five (7%) patients reported aggravation of seizures which led to CBD withdrawal. In addition, we observed improvement in behavior and alertness, language, communication, motor skills and sleep. Adverse reactions included somnolence, fatigue, gastrointestinal disturbances and irritability leading to withdrawal of cannabis use in 5 patients. CONCLUSIONS: The results of this multicenter study on CBD treatment for intractable epilepsy in a population of children and adolescents are highly promising. Further prospective, well-designed clinical trials using enriched CBD medical cannabis are warranted. Read the full study here http://www.seizure-journal.com/article/S1059-1311(16)00005-4/fulltext
  6. According to the new law passed by the Colorado government doctors can prescribe medical marijuana for patients suffering from cancer, HIV and AIDS, glaucoma, PTSD or other chronic medical condition that causes, nausea, severe pain, and seizures. The new law includes all medical conditions in which opioids could be recommended. https://www.myhealthyclick.com/colorado-passes-bill-that-allows-physicians-to-prescribe-medical-marijuana-rather-than-opioids/
  7. We've known for forty years that Cannabidiol (CBD) from the Cannabis Sativa aka Marijuana aka Hemp plant vastly reduces many different kinds of seizures and epilepsy in humans. It is a travesty that patients and parents of children with epilepsy are prohibited from using this non-toxic plant to prevent and stop seizures. Tens of thousands of epileptics have died because they were unable to access this life saving safe non-toxic medication. Abstract In phase 1 of the study, 3 mg/kg daily of cannabidiol (CBD) was given for 30 days to 8 health human volunteers. Another 8 volunteers received the same number of identical capsules containing glucose as placebo in a double-blind setting. Neurological and physical examinations, blood and urine analysis, ECG and EEG were performed at weekly intervals. In phase 2 of the study, 15 patients suffering from secondary generalized epilepsy with temporal focus were randomly divided into two groups. Each patient received, in a double-blind procedure, 200-300 mg daily of CBD or placebo. The drugs were administered for along as 4 1/2 months. Clinical and laboratory examinations, EEG and ECG were performed at 15- or 30-day intervals. Throughout the experiment the patients continued to take the antiepileptic drugs prescribed before the experiment, although these drugs no longer controlled the signs of the disease. All patients and volunteers tolerated CBD very well and no signs of toxicity or serious side effects were detected on examination. 4 of the 8 CBD subjects remained almost free of convulsive crises throughout the experiment and 3 other patients demonstrated partial improvement in their clinical condition. CBD was ineffective in 1 patient. The clinical condition of 7 placebo patients remained unchanged whereas the condition of 1 patient clearly improved. The potential use of CBD as an antiepileptic drug and its possible potentiating effect on other antiepileptic drugs are discussed. https://www.ncbi.nlm.nih.gov/pubmed/7413719 Abstract A high dose of Δ⁹-tetrahydrocannabinol, the main Cannabis sativa (cannabis) component, induces anxiety and psychotic-like symptoms in healthy volunteers. These effects of Δ⁹-tetrahydrocannabinol are significantly reduced by cannabidiol (CBD), a cannabis constituent which is devoid of the typical effects of the plant. This observation led us to suspect that CBD could have anxiolytic and/or antipsychotic actions. Studies in animal models and in healthy volunteers clearly suggest an anxiolytic-like effect of CBD. The antipsychotic-like properties of CBD have been investigated in animal models using behavioral and neurochemical techniques which suggested that CBD has a pharmacological profile similar to that of atypical antipsychotic drugs. The results of two studies on healthy volunteers using perception of binocular depth inversion and ketamine-induced psychotic symptoms supported the proposal of the antipsychotic-like properties of CBD. In addition, open case reports of schizophrenic patients treated with CBD and a preliminary report of a controlled clinical trial comparing CBD with an atypical antipsychotic drug have confirmed that this cannabinoid can be a safe and well-tolerated alternative treatment for schizophrenia. Future studies of CBD in other psychotic conditions such as bipolar disorder and comparative studies of its antipsychotic effects with those produced by clozapine in schizophrenic patients are clearly indicated. (PsycINFO Database Record (c) 2016 APA, all rights reserved) http://psycnet.apa.org/record/2006-05687-001 Abstract BACKGROUND The Dravet syndrome is a complex childhood epilepsy disorder that is associated with drug-resistant seizures and a high mortality rate. We studied cannabidiol for the treatment of drug-resistant seizures in the Dravet syndrome. METHODS In this double-blind, placebo-controlled trial, we randomly assigned 120 children and young adults with the Dravet syndrome and drug-resistant seizures to receive either cannabidiol oral solution at a dose of 20 mg per kilogram of body weight per day or placebo, in addition to standard antiepileptic treatment. The primary end point was the change in convulsive-seizure frequency over a 14-week treatment period, as compared with a 4-week baseline period. RESULTS The median frequency of convulsive seizures per month decreased from 12.4 to 5.9 with cannabidiol, as compared with a decrease from 14.9 to 14.1 with placebo (adjusted median difference between the cannabidiol group and the placebo group in change in seizure frequency, −22.8 percentage points; 95% confidence interval [CI], −41.1 to −5.4; P=0.01). The percentage of patients who had at least a 50% reduction in convulsive-seizure frequency was 43% with cannabidiol and 27% with placebo (odds ratio, 2.00; 95% CI, 0.93 to 4.30; P=0.08). The patient’s overall condition improved by at least one category on the seven-category Caregiver Global Impression of Change scale in 62% of the cannabidiol group as compared with 34% of the placebo group (P=0.02). The frequency of total seizures of all types was significantly reduced with cannabidiol (P=0.03), but there was no significant reduction in nonconvulsive seizures. The percentage of patients who became seizure-free was 5% with cannabidiol and 0% with placebo (P=0.08). Adverse events that occurred more frequently in the cannabidiol group than in the placebo group included diarrhea, vomiting, fatigue, pyrexia, somnolence, and abnormal results on liver-function tests. There were more withdrawals from the trial in the cannabidiol group. CONCLUSIONS Among patients with the Dravet syndrome, cannabidiol resulted in a greater reduction in convulsive-seizure frequency than placebo and was associated with higher rates of adverse events. (Funded by GW Pharmaceuticals; ClinicalTrials.gov number, NCT02091375.) http://www.nejm.org/doi/full/10.1056/NEJMoa1611618 Muskegon mom hopes medical pot will save daughter, 5 Nina DeSarro, WZZMPublished 9:08 a.m. ET March 1, 2018 Can medical marijuana save Michigan girl? Could something so taboo, something the federal government doesn't recognize as containing medicinal value, be the cure for a 5-year-old girl in Muskegon? (Photo: WZZM) LeAnne Parker is a supermom. Between caring for her two daughters, her dogs and keeping up with her career, she does it all. “For four years my life was normal. My kids were normal. I knew nothing was wrong,” Parker said. That is until January 7, 2017 when her five-year-old daughter, Lily became unresponsive. “Her eyes just slowly start going to the right, almost like poltergeist, to the point where she turned her whole body until she was facing the shower which was behind her,” Parker said. In a panic, Parker immediately called an ambulance. “I didn’t know what to do, I just sat there and cried, I thought I was losing her, I just had the door open and I was just screaming for somebody to please help,” Parker remembered. Lily was taken to the hospital where doctors couldn't figure out what had happened. “They just said, 'if it happens again call us' and sent me home with no answers so we came home with no answers,” Parker said. Two weeks later, it happened again. And then again. “She did testing and testing and everybody said ‘I don’t know, just the brain is…welcome to the brain,’” Parker said. Finally in February, Lily received a diagnosis of epilepsy. “With two seizures that are unprovoked, you get the diagnosis of epilepsy.” She was immediately put on prescription medication, but the seizures continued. Lily had reached the maximum dosage possibly. “Now she’s failed all pharmaceuticals,” Parker said. Not only were the medications ineffective, her physical and mental state began to deteriorate. Five-year-old Lily was high, every day, her mom said. “I sent her to school the other day, and they called me and they said that she was tired. She was passing out. She fell asleep during circle,” Parker said. She picked Lily up from school after her teachers told her she was walking into walls. The only other option for Lily was brain surgery, if she would even qualify. “I thought, there has to be something else,” Parker said. Brain surgery could mean a loss of Lily’s peripheral vision. “And there’s a chance that it wouldn't even work, so then my daughter is partially blind and still has seizures, how do you make that choice for your kid, I don’t know,” Parker said. She would never be able to drive, never be able to play sports, that’s a really, really hard decision to make as a parent.” Desperate for another solution, Leanne found out about CBD, Cannabidiol. “I started doing my research so instead of doing all of my research about epilepsy, now I was doing all of my research about CBD oil and learning everything I possibly could to learn about the benefits of it,” Parker said. She went to a meeting in Grand Haven about medical marijuana’s use in treating epilepsy and from that point forward, she was going to give CBD a try. “It’s my daughter, so you can judge me. I feel like we live in a culture where it’s okay to pop Oxycontin, Vicodin and pain killers but we look at CBD oil like it’s awful, I don’t understand that,” Parker said. Nervous, Leanne approached her daughter’s neurologist with the idea. “I brought it up to my doctor hoping and praying that he was on board with it and a lot of people aren’t I’m lucky that I found a doctor that is, because if he wasn’t, I’d have to do it behind his back,” Parker said. Weeks later, she received Lily’s medical marijuana license in the mail. “The sad part is, there’s no doctor to talk to and that is the most frustrating part with me, because I’m like ‘okay I’m on board I want to do this, how, where, what do I do, how do I go about it and how do I even know how to dose my daughter?’” Parker said. Through her research, she found Bloom. The Ann Arbor based medical marijuana facility that offers doctor/patient consulting. “I wish this was option one before the pharmaceuticals, I wish I would have tried this first,” Parker said. It’s still a little too early today, but it’s been 25 days seizure free for Lily. “I am not hopping on a bandwagon of medical marijuana, I’m jumping off of the pharmaceutical bandwagon,” Parker said. So far, this is the longest Lily has gone without having a seizure since July of 2017. https://www.freep.com/story/news/local/michigan/2018/03/01/muskegon-medical-marijuana-leanna-parker/384280002/
  8. CBD raids Just as a landmark cannabidiol lawsuit headed to court this week, police in Tennessee carried out the largest known CBD raids in history: 23 businesses were closed and 21 individuals were cited for selling illegal marijuana products. The raids, largely at tobacco shops selling candies and vape pens containing CBD, happened outside Nashville. The raids didn’t sweep up any producers or processors, but they put the fledgling hemp industry in Tennessee on notice. Like other states, Tennessee allows hemp growing and CBD production and has a small but thriving extraction industry. But CBD possession in the Volunteer State is limited to those with certain medical conditions. “You bet this is going to spark a few bills” in the state legislature, said Harold Jarboe, a Tennessee hemp grower who wasn’t affected by the raids. “Tennessee has one of those ‘wink-wink, nudge-nudge’ CBD laws, so hopefully this will change that.” Until CBD’s legal status is clarified, Jarboe said, the hemp industry needs to avoid looking like it’s trying to appeal to children and maybe avoid even using the letters C-B-D. “We’re trying to make a health product, so we don’t do vapes, we don’t do candy,” Jarboe said. “We call it ‘hemp extract.’ It saves a lot of headaches.” https://mjbizdaily.com/week-review-alcohol-tobacco-enter-cannabis-sector-detroits-mmj-issues-tennessee-cbd-raids/ https://ag.ks.gov/docs/default-source/ag-opinions/2018/2018-005.pdf Federal appeals court hears hemp industry lawsuit challenging DEA’s position on CBD PUBLISHED: FEB 15, 2018, 5:24 PM • UPDATED: 3 DAYS AGO By Alicia Wallace, The Cannabist Staff The fate of a federal rule viewed by hemp advocates as an existential threat to their emerging industry is now in the hands of a three-judge panel. The 9th U.S. Circuit Court of Appeals in San Francisco heard oral arguments Thursday in the Hemp Industries Association’s petition challenging the U.S. Drug Enforcement Administration’s January 2017 rule creating a Controlled Substances Code Number for “marihuana extracts.” DEA officials claim the rule is administrative in nature and helps the agency better track research and meet international drug treaty requirements. Attorneys for a hemp industry trade association and hemp businesses argue that the DEA conflated the terms “marijuana” and “cannabis,” ultimately creating a rule that can be interpreted as scheduling cannabis and cannabinoids as illegal substances. They blame the rule for a rash of seizures of cannabidiol products. The DEA’s rule epitomizes “government overreach” and stands in opposition to intervening legislation, Robert Hoban, a Denver-based attorney representing the hemp industry, told the 9th Circuit Court judges. “There was a seismic shift in United States cannabis policy in 2014 with the enactment of the Farm Bill, specifically Section 7606, involving industrial hemp,” said Hoban, a principal of Hoban Law Group. “And that seems to have created some confusion, perhaps, with the Drug Enforcement Administration.” Hoban claimed that confusion extended to other federal, state and local enforcement agencies, which have since seized products such as hemp-derived, CBD-rich extracts. “We’ve seen this drug code utilized week after week since it’s enactment to seize, to cause criminal enforcement against lawful operators who require no DEA registration,” Hoban said. Sarah Carroll, an attorney for the U.S. Department of Justice, countered that the language of the rule, follow-up guidance and court briefings expressly state that the code number applies only to the controlled parts of the cannabis plant that are within the Controlled Substances Act definition of marijuana. “It does not apply at all to the parts that Congress exempted,” she said. If other enforcement agencies acted out of step with DEA-issued rules and guidance, the “remedy would be to challenge that seizure,” she said. The judges will review the arguments and briefs filed in the case, which include an amicus brief filed last month by 28 members of Congress. It could be months before an opinion is released, Hoban Law Group attorneys have said. Timeline Hemp Industries Association et al v. Drug Enforcement Administration December 2016: New DEA rule on extracts, CBD causes commotion in cannabis industry January 2017: Legal challenge filed against DEA’s new marijuana extract rule April 2017: Hemp lawsuit in federal court alleges DEA overstepped on “extracts” rule June 2017: DEA seeks dismissal of hemp industry lawsuit fighting drug code for “marihuana extracts” July 2017: With DEA digging in its heels on “marihuana extracts,” legality of CBD oil on trial in federal courts July 2017: DEA statement on CBD, hemp products and the Farm Bill July 2017: CW Hemp’s Joel Stanley says DEA position statement on CBD, hemp and Farm Bill “reckless and illegal January 2018: Hemp industry lawsuit challenging DEA’s position on CBD picks up support of 28 U.S. legislators https://www.thecannabist.co/2018/02/15/cbd-hemp-dea-marijuana-extracts-lawsuit-federal-appeals-court/99168/
  9. The hemp industry is fighting the DEA again for its right to sell hemp products, including CBD. The Drug Enforcement Agency and US Attorney Generals have spent considerable resources on hemp farmers, state hemp projects, even attacking, raiding and destroying hemp crops in Native American tribal land. Members of congress have joined in the lawsuit against the DEA. Does the DEA even know what it is doing? Why did Eric Holder say hemp was schedule 1, prosecute hemp growers his entire tenure, only to retire and say that the laws should be changed? In Olsen v Holder 2009, some interesting facts about scheduling were reported: DEA Clarifies Status of Hemp in the Federal Register in 2001. What if you are unable to determine from reading the label and from asking the manufacturer or distributor whether the product contains THC? In such circumstances, if you wish to err on the side of caution, you may freely dispose of the product. As stated in the rules that DEA published on October 9, 2001, anyone who has purchased a food or beverage product that contains THC has 120 days (until February 6, 2002) to dispose of the product without penalty under federal law. Wait, Marijuana is the leaves and flowers and hemp is the stalks and seeds? What? Defining “Industrial Hemp”: A Fact Sheet The federal Congressional Research Service issued a report March 2017. Hemp as an Agricultural Commodity Renée Johnson Specialist in Agricultural Policy March 10, 2017 What about Cannabidiol? Since the DEA has been attacking Cannabidiol hemp products, some states have been claiming CBD is illegal. Department of Public Health Position Statement CBD Product Availability in Iowa Nebraska AG issued a memo on Cannabidiol products. Indiana AG issued an opinion of CBD , while the Indiana Governor said stores will have 60 days to destroy or remove CBD products from its stores. The FDA tested some CBD products and found some products contained no CBD, some contained higher than .3% THC and other products fluctuated with percentages of CBD. Also, the FDA has stated that because CBD is being investigated as a new drug, it cannot be marketed as a dietary supplement. The FDA is ignoring history when it says CBD is a "new drug". CBD was an ingredient of Extract of Cannabis, a formulation in the US Pharmacopia dating back to 1851. The fight against hemp, marijuana, cannabis continues. https://mjbizdaily.com/congress-members-defend-cbd-blast-deas-hemp-decision/ Congress members defend CBD, blast DEA’s hemp decision Published January 12, 2018 | By Kristen Nichols In a bold show of support for the hemp industry and CBD, 28 members of Congress are asking a federal appeals court to reject the Drug Enforcement Administration’s argument that cannabidiol is a Schedule 1 drug. The Congress members filed the brief Thursday in conjunction with a pending lawsuit against the DEA. The 9th Circuit Court of Appeals is set to hear arguments in the case Feb. 15. The Congress members – 22 Democrats and six Republicans – argue that the DEA is “blatantly contrary” to the 2014 Farm Bill when it argues that CBD is a marijuana extract and therefore illegal. “The Farm Bill’s definition of industrial hemp includes any part of the plant, including the flower,” the Congress members argue in the brief. The members conclude that the federal agency’s rule about CBD was an “abuse of DEA’s administrative procedure and rulemaking authority.” The lawyer who wrote the brief for the Congress members, Steven Cash, told Marijuana Business Daily that Congress members took the extraordinary step of weighing in on the lawsuit in hopes of seeing the courts resolve the conflict between the Farm Bill and the DEA’s interpretation on the Controlled Substances Act. “Apart from arguing about the relative benefits, flaws and dangers of medical marijuana and hemp, it appears we’re going to solve this (conflict) through traditional avenues, the courts,” Cash said. The DEA said in late 2016 that because CBD cannot be easily extracted from non-flower parts of the cannabis plant, CBD should be considered a controlled substance. The decision brought a hasty lawsuit from the Hemp Industries Association and a CBD business. A lawyer for the hemp companies says the brief will show judges that Congress understood what it was doing when it authorized hemp production, meaning not just the stalks and seeds but the whole plant. “Congress has spoken, yet again,” Bob Hoban said in a statement. “The industrial hemp industry has seen exponential growth … and this case represents the most significant challenge the U.S. hemp industry has seen to date.”
  10. http://www.derbytelegraph.co.uk/news/derby-news/grandmother-says-cancer-almost-gone-967552 Grandmother says cancer has almost gone after taking cannabis oil - now she wants the Government to act She is now calling on the Government to fund trials of cannabis oil on patients waiting for cancer treatment By Cheryl Hague 07:00, 25 DEC 2017 A grandmother who had a malignant tumour in her breast which measured 33mm says it has now almost gone after taking cannabis oil. Now Lin Coxon, of Willington, is sharing her story with the Government to see if they will fund a medical trial testing cannabis oil on patients while they are waiting for cancer treatment. Lin was diagnosed with the disease on June 28 at the Royal Derby Hospital. A scan revealed the size of the lump and found it had also invaded her nearby lymph nodes. She was told her treatment would involve eight rounds of chemotherapy followed by a lumpectomy and the removal of all the lymph nodes. This would then have to be followed by radiotherapy. But while waiting for her treatment to start in August the 69-year-old read how, in some cases, cannabis oil had been found to help treat cancer so she bought some and began taking it. Incredibly her last scan revealed the cancer has completely gone from her lymph nodes and the tumour is hardly visible. Grandmother Lin Coxon told how a cancerous tumour discovered in her breast has shrunk from 33mm to 7mm in just a few weeks purely by taking CANNABIS oil She said doctors at the hospital are fascinated by her case and are continuing to monitor her progress even though she isn’t going ahead with the chemotherapy as they originally suggested. Lin said: "I feel fantastic and can tell it has almost gone. Before it felt like a hard lump but after a few weeks of taking the oil it had shrunk so much I couldn't feel it. Now it's almost gone and, on the scan, you could see how the density has changed from something that looked solid where now the only bit that is left looks like a tiny bit of smoke. "I bought cannabis oil from a health shop in Ashbourne and decided to take a few drops - I didn't have anything to lose as I was waiting for my chemotherapy to start so thought I may as well give it a try. I am so glad I did. "The doctors are still monitoring me and said if it did come back I would have to have chemotherapy and of course I would but I just want to see how it goes now. "In fact at my last appointment the doctors said the tumour was so small they could to a lumpectomy to get it out - but I said let's just see how the oil works for a bit longer. "Since I spoke of my initial success with the oil in The Derby Telegraph in October I have been contacted by other people who have had similar positive experiences so I really think there is something in it. "I cannot say cannabis oil will work for anyone else but my experience would seem to show it is worth trying. I feel people have nothing to lose especially if they are waiting for chemotherapy. It may only help for some cancers - we won't know though until research takes place." Lin Coxon bought the cannabis oil in Ashbourne Now Lin, who is Southern Derbyshire MP Heather Wheeler's personal assistant, wants the Government to take notice of her case and she has written to Steve Brine MP who is the Parliamentary Under-Secretary of State for Public Health and primary care asking about funding a trial in Derby which would allow patients diagnosed with cancer and waiting for treatment to take the oil in the meantime if they wanted to. Then the hospital could scan them before they had treatment to see if taking the oil has had any effect. She said: "I just think it has to be looked into further as more people could be helped without the need for medical intervention - and, if that is the case, it would also save the NHS a lot of money." The grandmother-of-ten, said she was inspired to try the cannabis oil after reading in The Derby Telegraph how it had helped Sinfin Asda worker Karen Roberts. She was sent home to die with terminal cancer but took the oil - and now two years later is in remission. Read her story here. Lin bought the oil, which is legal and sold minus the psychoactive component that causes a high, at a health shop in Ashbourne. It cost a £39 a bottle. She has a few drops each day and a bottle lasts her ten days. The oil has not yet been approved for use on the NHS - but is readily available to buy online as a food supplement - although it has been widely reported to help other conditions such as arthritis, depression and MS. Research into the health benefits of taking cannaboids - particularly for cancer - is currently being undertaken at St George's, University of London, and the medical experts there have been in contact with Lin. Dr Wai Liu, senior research fellow at St George's, University of London, said: “I was very interested to hear of Lin’s case. Cannabidiol, which is just one element of the cannabis plant and one that does not have any psychoactive effect on people, has been shown to target communication signals that are malfunctioning in cancer cells. “It is thought that, by correcting these signals, we can enable cancer cells to essentially die rather than duplicate. So it may hold the key to understanding how to defeat cancer in some areas. “We at St George's, University of London, have shown how this can be done. Although our data has mainly been laboratory- based, we have a growing and large collection of testimony from patients using cannabidiol, usually in a cannabis oil type product, who report positive effects on their battle with this dreadful disease. "Lin's story is one that adds to this growing list and we wish her all the best in her treatment which should always be under the supervision of her doctors.”
  11. http://www.independent.co.uk/news/health/cannabis-extract-marijuana-psychosis-treatment-mental-health-cbd-thc-cannabidiol-kcl-a8111386.html Psychosis is a mental health diagnosis characterised by hallucinated voices or visions, or delusions where patients have strong and unfounded beliefs, for example feeling there is a conspiracy to harm them. Antipsychotic drugs have been used in treating it for 60 years, but they have limited effectiveness and can have serious side-effects. Professor Philip McGuire, from King’s College London’s Institute of Psychiatry, Psychology and Neuroscience, was the lead author of the study. He said conventional drugs acted by blocking biological receptors for mood-altering chemical dopamine. “However, dopamine is not the only neurotransmitter whose function is altered in psychosis, and in some patients dopamine function may be relatively normal,” he added. “We need new classes of treatment that target different neurotransmitter systems.” This trial found that patients given a CBD treatment saw statistically significant improvements in their psychosis symptoms relative to a group given a placebo. The 83 patients, from the UK, Romania and Poland, also saw significant improvements in their health and severity of their illness as measured by their therapists. There were signs of better cognitive performance as well, but this was not statistically significant. While all the improvements were modest, the patients were still using their antipsychotic medication so it shows CBD treatments can offer additional benefits over and above conventional treatment. The results are published in the American Journal of Psychiatry today. The paper says: “This is, to our knowledge, the first placebo-controlled trial of CBD in schizophrenia. “The data indicate that six weeks of treatment adjunctive to antipsychotic medication was associated with significant effects both on positive psychotic symptoms and on the treating clinicians’ impressions of improvement and illness severity.” Professor McGuire added that larger trials were now needed to confirm these findings in other patient groups. “Although it is still unclear exactly how CBD works, it acts in a different way to antipsychotic medication, and thus could represent a new class of treatment. “Moreover, CBD was not associated with significant side effects. This is also potentially important, as patients may be reluctant to take antipsychotic medication because of concerns about side effects.” https://www.ncbi.nlm.nih.gov/pubmed/29241357 Read the study here. Professor McGuire was singing a different tune about this same study last year. https://www.medscape.com/viewarticle/862312 Lead investigator Philip McGuire, MD, PhD, Department of Psychosis Studies, Institute of Psychiatry Psychology and Neuroscience, Kings College London, United Kingdom, who presented the findings, acknowledged that the improvements with cannabidiol were not dramatic. However, he told Medscape Medical News: "The way I would look at it is that it's quite hard to see an effect in people who are already being treated with something else. Dr Philip McGuire "I would guess that if you didn't have them on antipsychotics, the scope for an improvement would be even greater, because the baseline symptoms would be higher, so it should be easier to show a bigger change." Noting the lengthy discussion of the data that followed his talk, Dr McGuire said: "Somebody in the audience pointed out that there was a previous trial which compared cannabidiol on its own with an antipsychotic and showed that cannabidiol had the same magnitude of effect as an antipsychotic. That shows that the [effect with] monotherapy is at least as big as an antipsychotic." The patients were randomly assigned in a double-blind fashion to cannabidiol 1000 mg/day oral solution, 500 mg twice daily, or matched placebo for 6 weeks and were assessed on intention-to- treat analysis. 1 gram CBD per day. http://alert.psychnews.org/2017/12/cannabidiol-may-be-effective-adjunct-to.html CBD was well tolerated, and rates of adverse events were similar between the CBD and placebo groups. Please always know where your CBD comes from. Have your CBD tested for purity and accurate dosage / strength. https://jamanetwork.com/journals/jama/article-abstract/2661569 There is growing consumer demand for cannabidiol (CBD), a constituent of the cannabis plant, due to its purported medicinal benefits for myriad health conditions. Viscous plant derived extracts, suspended in oil, alcohol (tincture), or vaporization liquid, represent most of the retail market for CBD. Discrepancies between federal and state cannabis laws have resulted in inadequate regulation and oversight, leading to inaccurate labeling of some products. To maximize sampling and ensure representativeness of available products, we examined the label accuracy of CBD products sold online, including identification of present but unlabeled cannabinoids. Read the study here.
  12. Israel -- Scientists in Israel are exploring another medical use for marijuana: Their research indicates that a compound in the plant helps heal bone fractures. The new study, published in the Journal of Bone and Mineral Research, found that broken bones healed faster and stronger when the patient received the non-psychoactive compound cannabidiol, or CBD. Read More...
  13. Cannabis Planet.TV http://vimeo.com/83094404 <iframe src="//player.vimeo.com/video/83094404" width="500" height="281" frameborder="0" webkitallowfullscreen mozallowfullscreen allowfullscreen></iframe> <p><a href="http://vimeo.com/83094404">Dr. Christina Sanchez</a> from <a href="http://vimeo.com/user15519688">Cannabis Planet</a> on <a href="https://vimeo.com">Vimeo</a>.</p>
  14. Drug Maker Secures Patent on THC and CBD as Cancer Treatment A pharmaceutical company in the United Kingdom, specializing in the research and development of pot-based drugs, recently obtained early approval on a patent covering two specific cannabinoids found in marijuana to be used as treatment for brain cancer. According to a press release, GW Pharmaceuticals will hold the patent rights to the two primary compounds found in marijuana, THC and CBD, for use as medicine for patients suffering from gliomas -- the most common form of malignant brain tumor. The United States Patent Office informed the drug company earlier last week, by way of Notice of Allowance, that a patent application filed several years ago was officially deemed a genuine invention and is now in its final stages of approval. GW Pharmaceuticals must now submit the appropriate fees before final approval for their cancer combatant patent is granted. Try saying that five time fast. “The subject patent specifically covers a method for treating glioma in a human using a combination of cannabidiol (CBD) and tetrahydrocannabinol (THC) wherein the cannabinoids are in a ratio of from 1:1 to 1:20 (THC:CBD) with the intent to reduce cell viability, inhibit cell growth or reduce tumor volume,” according to a statement issued by the company. GW’s patent application was originally filed in 2009, which detailed the company’s invention of the “use of a combination of cannabinoids in the manufacture of a medicament for use in the treatment of cancer.” Yet, it is believed the verbiage was revised at some point, noting more specific information, including THC and CBD ratios and the fact that the treatment is used against brain cancer. Justin Gover, GW’s Executive Chief Officer, says that the company recently initiated its first wave of clinical trails to study glioma, a disease that accounts for nearly 50% of new brain cancer diagnoses in the United States each year. “The treatment of glioma is part of our exciting new orphan drug program which includes a number of therapeutic targets and demonstrates the flexibility of GW’s proprietary cannabinoid platform in treating a broad range of disease types.”
  15. 13 Things You May Not Know About Cannabis By Laurel Dewey 1. Smoking marijuana is actually the least effective way to benefit from the medicinal power of marijuana. Opt for liquid extracts, cannabis butters or medicated oils to truly gain the deepest use from this healing plant. 2. The term “marijuana” is actually a Mexican slang term that the U.S. government bestowed on the cannabis plant in the 1930’s. The true name of the plant is simply: cannabis. 3. In all of recorded history, nobody has ever died from consuming or smoking marijuana. 4. The two main medicinal species are Cannabis Sativa and Cannabis Indica. Sativas affect the mind more and are more exhilarating while the Indicas work more on the body, providing physical relief and relaxation. 5. The term cannabinoids refers to the multiple compounds found within the marijuana plant. Cannabis has over sixty known cannabinoids, many of which have not been thoroughly studied. What people may not realize is that we were all born with cannabinoid receptors in our brains, liver, stomach and nerve tissue, making us human sponges to soak up the benefits of cannabis. 6. Marijuana liquid extracts were routinely given to babies in the late 1800’s and early 1900’s to effectively combat teething pain. 7. There are single strains of marijuana that can help you sleep, reduce pain, relieve muscle spasms and calm the mind. In other words, one marijuana strain can take the place of four different drugs, eliminating the multiple side effects of the pharmaceuticals. 8. Queen Victoria regularly depended upon cannabis indica extracts to ease her menstrual cramps. 9. Most people have heard about THC, the main psychoactive constituent in marijuana. However, there is another very important element in the plant called CBD that is non-psychoactive. Breeders are creating high CBD marijuana strains that have less than 1% of THC, making them non-psychoactive. High CBD marijuana has been shown to be excellent for stress, anxiety, inflammation and reducing the spread of cancerous tumors. 10. A 1974 conducted at the University of Virginia discovered that the cannabinoids in cannabis shrunk cancerous tumors and killed cancer cells, leaving the healthy cells alone. 11. Contrary to the propaganda that “pot kills brain cells,” research has shown that marijuana can actually protect brain cells, even when those cells have damaged by chronic alcohol abuse. In addition, marijuana has been shown to slow the progression of Alzheimer’s Disease, Parkinson’s Disease and protect victims of epilepsy, strokes and severe head trauma due to what appears to be neurogenesis—it’s ability to grow new nerves in the brain. 12. Marijuana seeds produce both male and female plants. However, the medicinal bud only is found on the female plants. 13. You don’t have to ingest marijuana to benefit from its healing abilities. Marijuana buds and leaves can be melted into oils and cocoa butters to make potent topical pain killing ointments that do not get you high. Betty’s (Little Basement) Garden tells the story of one woman’s path to self-discovery about who she really is. What happens when you turn your back on everything that you believed? Follow Betty on her journey from an anti-cannabis staunch Republican to a pro-cannabis free spirit. For more information on the book, please visit the following website: www.TheStoryPlant.com - The book will be released on June 12, 2012. Trix
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