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Endocannabinoid System Enhanced By Vitamin E


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Could eating a better diet make for a better cannabinoid experience? The journal of Free Radical Biology and Medicine published a report, which identifies vitamin E as a “modulator of the cannabinoid system.”

 

Alpha-Tocopheral is considered the main ingredient of vitamin E, and is well known for its anti-oxidant properties and mood elevating abilities. Low levels of alpha-tocopheral in the brain are associated with health issues such as depression and neuronal degradation.

 

The authors demonstrated that the actions of vitamin E can be blocked, if the cannabinoid type 1 receptor is blocked by a drug AM251. AM251 can block cannabinoid receptors and prevent them from being activated.

 

The authors report that the vitamin E and cannabinoid receptor interactions are occurring in a region of the brain known as the hippocampus, which may help explain the benefits of vitamin E other than its anti-oxidant properties.

 

Vitamin E can have profound effects on brain function, and it is widely used as a food additive. Without vitamin E in the diet a number a symptoms can start to appear, such as anxiety or ataxia.

 

However, vitamin E does not directly activate cannabinoid receptors, like for example THC, instead alpha-tocopheral modulates the receptor. The receptor modulation from alpha-tocopheral may be an important part of normal cannabinoid receptor function. More research is need to fully understand exactly how alpha-tocopheral obtained from the diet can influence the cannabinoid system.

 

High-calorie, inexpensive, high-fat and nutritionally deficient diets are common in the United States. These bad diets are correlated to obesity and brain disease. A balance of omega-3 fatty acids or vitamin E can help us live longer and healthier. The mechanism of this wonderful benefit is due to an integrated response between these lipids such as from alpha-tocopheral and cannabinoid receptors.

 

We ask ourselves the same questions as before; Can our diet can influence our response to cannabinoids and Cannabis? Could the negative effects of cannabinoids be related to nutritionally-deficient diets, which are also associated with mental diseases, such as depression?

 

This study raises a number of radical ideas that warrant further studies.

 

By the way…pumpkins have a good amount of vitamin E for some (possible) seasonal cannabinoid receptor system adjustments!

 

 

http://www.bayareacannabis.org/?p=887

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When I did have a garden pumpkins grew very well here in South Eastern Michigan . It was nice to grow up in Ann Arbor City Limits we had community gardens back in the 70's and I remember being involved in projects associated with the first Earth Day . In one they drained the Huron River from Pinkney to Argo dam then , citizens walked and cleaned the entire riverbed . Afterword they then re flooded it and stocked it with the fish people catch today . I remember people finding model t's and all sorts of things . I had many old bottles from the Ann Arbor Bottle Works of the Civil War era . Several people on the program now were involved doing all sorts of community service .

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When I did have a garden pumpkins grew very well here in South Eastern Michigan . It was nice to grow up in Ann Arbor City Limits we had community gardens back in the 70's and I remember being involved in projects associated with the first Earth Day . In one they drained the Huron River from Pinkney to Argo dam then , citizens walked and cleaned the entire riverbed . Afterword they then re flooded it and stocked it with the fish people catch today . I remember people finding model t's and all sorts of things . I had many old bottles from the Ann Arbor Bottle Works of the Civil War era . Several people on the program now were involved doing all sorts of community service .

 

Thank you! :bighug:

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