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The Therapeutic Potential Of Cannabis

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I spend a lot of my time on this computer (to much). I like to look up things like medicinal plants and from time to time I run across something neat and today, this is it.





Dtsch Arztebl Int. 2012 Jul;109(29-30):495-501. Epub 2012 Jul 23.

The therapeutic potential of cannabis and cannabinoids.


Grotenhermen F, Müller-Vahl K.




nova-Institut GmbH, Chemiepark Knapsack, Hürth.






Cannabis-based medications have been a topic of intense study since the endogenous cannabinoid system was discovered two decades ago. In 2011, for the first time, a cannabis extract was approved for clinical use in Germany.



Selective literature review



Cannabis-based medications exert their effects mainly through the activation of cannabinoid receptors (CB1 and CB2). More than 100 controlled clinical trials of cannabinoids or whole-plant preparations for various indications have been conducted since 1975. The findings of these trials have led to the approval of cannabis-based medicines (dronabinol, nabilone, and a cannabis extract [THC:CBD=1:1]) in several countries. In Germany, a cannabis extract was approved in 2011 for the treatment of moderate to severe refractory spasticity in multiple sclerosis. It is commonly used off label for the treatment of anorexia, nausea, and neuropathic pain. Patients can also apply for government permission to buy medicinal cannabis flowers for self-treatment under medical supervision. The most common side effects of cannabinoids are tiredness and dizziness (in more than 10% of patients), psychological effects, and dry mouth. Tolerance to these side effects nearly always develops within a short time. Withdrawal symptoms are hardly ever a problem in the therapeutic setting.



There is now clear evidence that cannabinoids are useful for the treatment of various medical conditions.


In my mind, this conclusion should be the death of schedule I. You couple this with the fact that the United States Government owns patents on certain cannabinoids and bingo, no schedule I. So now, tell me, how can Cannabis remain on the DEA's schedule I?


There are 484 different studies on cannabis listed on the above web site. This will amaze your viewing pleasures because I only looked at the first dozen or so studies and they seem to be overwhelmingly favorable to our cause. I hope this is introduced as evidence at the ASA vs DEA trial. Just about any half educated person could schedule cannabis correctly. It is sorta like our neighboring police force in Canada can distinguish hemp from cannabis and our leo haven't got a clue.

Edited by Herb Cannabis
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