Atomizer Spray

[in vivo]

Anyone ever use the propylene glycol/EtOH (50/50), like Sativex, in an atomizer spray bottle for sublingual application?

 

Care to share your experiences?

[in vivo]

Anyone have any experience with these?

 

I'm wondering about delivery amounts per spray. Sativex is THC 2.7mg/CBD 2.5mg (I think), but I have to wonder how seasoned the patients involved in their research were. If I account for tolerance, I'm wondering if I should be as high as 20mg per spray. Anyone here have any experience?

[I wood]

80% alcohol 20% water worked for my patients. A little harsh  for some, no issues for most.

A little cinnamon and sugar  was  the most popular flavor.

One gram rso in a two ounce spray bottle delivered about 5 mgs per pump/spray.

[in vivo]

Thanks for you input.

 

Did you experiment with propylene glycol or glycerin?

[I wood]

no

[in vivo]

I've been playing around with:

EtOH/glycerin

EtOH/propylene glycol

glycerin/propylene glycol

 

I think EtOH/glycerin tastes the best, but I'm assuming that EtOH/propylene glycol will be most effective. EtOH or propylene glycol on their own have an unpleasant taste, but for some reason when they're mixed together it's not half as bad imo.   

[in vivo]

 

These are 4ml atomizer spray bottles.

 

There's 55-60 sprays per bottle. The bottle on the right has 500mg (8.33-9.09mg per spray) of concentrate. The one on the left has 300mg (5-5.45mg per spray)

 

The concentrate is suspended in 1:1 ration of EtOH/propylene glycol.

 

I plan to play around with terpenes to find some that are therapeutically beneficial and palatable. I also plan to add magnolia extract.

 

I know a patient that has issues with pain, has been through a number of pharmaceuticals, and after reluctantly trying, has found some relief from cannabis. The issue is that this person doesn't enjoy the act of smoking or the intensity of the high. For a patient like this, sublingual delivery methods are likely the best option. This person should be able to maintain a steady level of cannabinoids to treat the pain, but at the same time there shouldn't be an overwhelming activation of CB1 that can sometimes lead to experiencing a sense of anxiousness. 

Edited August 26, 2013 by in vivo

[in vivo]

I played around with some LorAnne Oils (used for flavoring hard candy). I don't recommend it.

 

I'm finding it to be a challenge identifying palatable flavors that go with propylene glycol.