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Medical marijuana for the treatment of epilepsy has been a controversial and intriguing topic for the last few years. Drawing upon both clinical experience and research findings, the panelists discuss the potential medical benefits and risks of using medical marijuana as a treatment for epilepsy. The panelists also review the legal and practical issues associated with medical marijuana use in Michigan.

Panelists: Evangelos Litinas, MD, MBA – Om of Medicine; Gregory Barkley, MD – Henry Ford Comprehensive Epilepsy Center; Zahra Abbas – Adult with Epilepsy; Michael Komorn – Komorn Law, Michigan Medical Marijuana Association

 

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Published on Mar 1, 2018

Muskegon Mother finds non-toxic and safe Cannabidiol CBD from medical marijuana is a better treatment for epilepsy than liquid Valium.

In phase 1 of the study, 3 mg/kg daily of cannabidiol (CBD) was given for 30 days to 8 health human volunteers. Another 8 volunteers received the same number of identical capsules containing glucose as placebo in a double-blind setting. Neurological and physical examinations, blood and urine analysis, ECG and EEG were performed at weekly intervals. In phase 2 of the study, 15 patients suffering from secondary generalized epilepsy with temporal focus were randomly divided into two groups. Each patient received, in a double-blind procedure, 200-300 mg daily of CBD or placebo. The drugs were administered for along as 4 1/2 months. Clinical and laboratory examinations, EEG and ECG were performed at 15- or 30-day intervals. Throughout the experiment the patients continued to take the antiepileptic drugs prescribed before the experiment, although these drugs no longer controlled the signs of the disease. All patients and volunteers tolerated CBD very well and no signs of toxicity or serious side effects were detected on examination. 4 of the 8 CBD subjects remained almost free of convulsive crises throughout the experiment and 3 other patients demonstrated partial improvement in their clinical condition. CBD was ineffective in 1 patient. The clinical condition of 7 placebo patients remained unchanged whereas the condition of 1 patient clearly improved. The potential use of CBD as an antiepileptic drug and its possible potentiating effect on other antiepileptic drugs are discussed.
 

 

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