Rat Parents Who Get Thc, Leads To Compulsive Heroin-Seeking In Their Offspring, Rat Study Says.

[t-pain]

http://www.ncbi.nlm.nih.gov/pubmed/23954491

 

Here, we show that adolescent exposure to Δ9-tetrahydrocannabinol (THC), the main psychoactive component of cannabis, results in behavioral and neurobiological abnormalities in the subsequent generation of rats as a consequence of parental germline exposure to the drug.

 

should play bingo with these studies. does it compare marijuana to heroin? check!

 

[trichcycler]

I would never give thc to a rat. good to not be a part of ruining their offspring.

[Wild Bill]

Here's an interesting twist on experiments with rats. Worth checking out.

 

http://www.stuartmcmillen.com/comics_en/rat-park/

 

 

[t-pain]

yes these behavior studies in rats turn out to be bunk a lot.

 

good to see the prohibitionists working hard still. wouldnt want them to quit yet.

[jamf]

sad pic of caged rat.

 

Studies have shown that morphine help rat's learned helplessness and depression.  They never talk about the anti-depressant effects of morphine.  They only see whatever result theyre looking for.

 

They did a similar cocaine study with monkeys.  They were caged in a group, so they still socialized.  They couldn't get the monkeys hooked on coke.  They would avoid it.  Whereas the monkey trapped in a the cage injested coke till it died.

Edited January 24, 2014 by jamf

[phartat]

It may not be the pot. THC does not dissolve well in H2O, but new means to dissolve THC in water were developed in the late 90's, it involves encapsulating the THC molecules in other chemicals. This is important because the THC was administered intravaniously.
 

Cyclodextrins - Used to aid the in the solubility in medicines not normally soluble in water.

"The safety profiles of CDs are discussed, with emphasis on the biological effects of some CDs on the gastrointestinal tract, kidney, and reproduction and development and the carcinogenic potential of CDs"

http://tpx.sagepub.com/content/36/1/30.full

"Piroxicam-beta-cyclodextrin produces potentially life-threatening effects which include GI bleeding, Aplastic Anemia, Renal damage, Peptic ulceration, Purpura, Pemphigus vulagris. which are responsible for the discontinuation of Piroxicam-beta-cyclodextrin therapy."

http://druginfosys.com/Drug.aspx?drugCode=2177&drugName=Piroxicam-beta-cyclodextrin&type=7

So we can see here that the THC compound has been alduterated and this study is inherently flawed. The birth defects might be due to the Cyclodextrins just as some of the negative side effects of Piroxicam-beta-cyclodextrin may be caused by the beta-cyclodextrin and not the Piroxicam itself. For instance, both negatively affect the GI and the CD's are the common denominator.

Edited January 25, 2014 by phartat

[trichcycler]

I'm all outta likes for the day, but this is interesting info, thanks much

It may not be the pot. THC does not dissolve well in H2O, but new means to dissolve THC in water were developed in the late 90's, it involves encapsulating the THC molecules in other chemicals. This is important because the THC was administered intravaniously.

Cyclodextrins - Used to aid the in the solubility in medicines not normally soluble in water.

"The safety profiles of CDs are discussed, with emphasis on the biological effects of some CDs on the gastrointestinal tract, kidney, and reproduction and development and the carcinogenic potential of CDs"

http://tpx.sagepub.com/content/36/1/30.full


"Piroxicam-beta-cyclodextrin produces potentially life-threatening effects which include GI bleeding, Aplastic Anemia, Renal damage, Peptic ulceration, Purpura, Pemphigus vulagris. which are responsible for the discontinuation of Piroxicam-beta-cyclodextrin therapy."

http://druginfosys.com/Drug.aspx?drugCode=2177&drugName=Piroxicam-beta-cyclodextrin&type=7

So we can see here that the THC compound has been alduterated and this study is inherently flawed. The birth defects might be due to the Cyclodextrins.

[Mr. Wilson]

I smell a rat!

 

Something makes me wonder why someone would even bother doing a RAT study on this issue, when you could easily do a human study...hmmmm???

 

Maybe the rat study supported their preconceived notions, making the human study unnecessary?

 

My next rat study involves injecting caged Republicans with THC, to see if some type of shared common sense can be extracted.

[t-pain]

most all of the anti cancer, anti tumor studies are done on rats too.

 

but rat behavior studies are often flawed. you cant cage an animal and then study its behavior patterns. behavior is tainted due to the cage.

 

its like studying someone in solitary confinement in prison and then claiming to have figured out how all humans behave.

it just doesnt work like that.

[trichcycler]

Rats work cheaper than college kids wandering into drug research trials maybe