Jump to content

Recommended Posts

Posted

thanks for the share!

 

#5=5.Given that people using CBD-rich cannabis for “general wellbeing” are the only group who reported a decreased feeling of wellbeing and the most likely to report a worsening mood, it's possible that CBD products may not be appropriate as a supplement for people who are otherwise healthy.

 

 

like dosing antidepressants to someone who does not have brain chemical issues maybe?

 

I cant find the definition of "CBD Rich" ?

Posted (edited)

added to this report from the same webby I bet this stuff gets lots of attention


 

CBD and other plant cannabinoids can potentially interact with many pharmaceuticals by inhibiting the activity of cytochrome P450, a family of liver enzymes. This key enzyme group metabolizes most of the drugs we consume, including more than 60 percent of marketed meds.

At sufficient dosages, CBD will temporarily deactivate cytochrome P450 enzymes, thereby altering how we metabolize a wide range of compounds, including tetrahydrocannabinol (THC), which causes the high that cannabis is famous for.

https://www.projectcbd.org/article/cbd-drug-interactions-role-cytochrome-p450
 
and these "common misconceptions"
 


3.“CBD is most effective without THC.” THC and CBD are the power couple of cannabis compounds—they work best together. Scientific studies have established that CBD and THC interact synergistically to enhance each other’s therapeutic effects. British researchers have shown that CBD potentiates THC’s anti-inflammatory properties in an animal model of colitis. Scientists at the California Pacific Medical Center in San Francisco determined that a combination of CBD and THC has a more potent anti-tumoral effect than either compound alone when tested on brain cancer and breast cancer cell lines. And extensive clinical research has demonstrated that CBD combined with THC is more beneficial for neuropathic pain than either compound as a single molecule.

1.“CBD is medical. THC is recreational.”

2.“THC is the bad cannabinoid. CBD is the good cannabinoid.”



4.“Single-molecule pharmaceuticals are superior to ‘crude’ whole plant medicinals.”
5.Psychoactivity is inherently an adverse side effect.”

6.“CBD is legal in all 50 states.”

7.“'CBD-only’ laws adequately serve the patient population.”

8.“CBD is CBD—It doesn’t matter where it comes from.”

 


https://www.cbd.org/sites/cbd/files/downloads/cbdpatientsurvey_september2015_carebydesign.pdf



Great Thread!

Edited by grassmatch
Posted

The cannabis industry has witnessed an internal arms race in recent years, with marijuana growers and infused products companies trying to top each other by boosting THC levels in their offerings to new heights.

But another trend has emerged on the other end of the spectrum as well. Cannabis businesses are developing an ever-increasing array of products that contain high amounts of CBD, catering to increased demand from users who want to ease pain without getting high.

The sharp rise in interest among cannabis users can be seen in data from the strain and dispensary review site Leafly, which had over 40 million total visitors in 2014 and projects over 70 million in 2015. Currently, the site has a little over 1 million registered users.

In July, Leafly recorded 1,770 unique searches for the term “CBD” on its site and mobile app, a 521% increase from August 2014, according to data provided by the company on its top 150 search terms over that 12-month period. CBD also is now one of the top 50 terms users search for each month.

The figures support what many in the industry have already observed: interest among both medical and recreational users in CBD has skyrocketed.

FS-Sally-Vander-Veer.png“The whole original intent (with high-CBD products) was to help patients manage their pain,” said Bruce Nassau, CEO and partner of Tru Cannabis, which operates five marijuana storefronts in Colorado. “Now, recreational users have picked up on this, and rather than go for opiates that are prescribed by a medical provider, they are essentially starting to self-medicate.”

Nassau described how the majority of increased demand at Tru Cannabis’ locations has initially been for high-CBD flowers, but that demand for high-CBD edibles and topicals has picked up significantly as well.

“(High-CBD) patches in particular have gotten really popular,” he said.

Cannabidiol’s pain and seizure management properties are well known within the MMJ community, but the newly legal recreational markets have brought a much wider array of cannabis users into the fold. Nassau likened this phenomenon to that of the “diffusion of innovation” and stated the MMJ community are essentially the early adopters of high-CBD forms of the plant, but use of such products will ultimately become mainstream.

“The (increased) demand for high-CBD really drove us to offer these products on the rec side,” where they have been immensely popular, he said.

It’s worth noting the large spike in searches on Leafly for “CBD” in July is tied mostly to user activity on the company’s mobile app, as searches for the term on its website were relatively flat.

This indicates an even more recent shift in when and how patients and consumers are searching for information about cannabis, as well as how they seek out retail outlets with high-CBD products.

High rates of activity on mobile apps for marijuana are generally associated with younger consumers, indicating a spike in interest for high-CBD products among users whose use is more typically associated with partying.

As the marijuana industry evolves, so too does the face of the “typical” cannabis user, particularly in states that permit recreational sales. The acceleration of interest in therapeutic uses of CBD is another indicator of that evolution.

Becky Olson can be reached at beckyo@mjbizmedia.com

Posted

“The whole original intent (with high-CBD products) was to help patients manage their pain,” said Bruce Nassau, CEO and partner of Tru Cannabiswhich operates five marijuana storefronts in Colorado. “Now, recreational users have picked up on this, and rather than go for opiates that are prescribed by a medical provider, they are essentially starting to self-medicate.”

 

 

I call BS on this. An unusually highly stinkin' variety of it, but BS all the same.  Recreational users are not hunting for high CBD strains. Please quit insulting our intelligence Bruce. Find some other way to lie for money. 

Posted

High rates of activity on mobile apps for marijuana are generally associated with younger consumers, indicating a spike in interest for high-CBD products among users whose use is more typically associated with partying.

 

Make up your mind Bruce, CBD either gets you high or it does not. You can't have/say it both ways or you sound like a moron. Partying equals getting high. 

Posted

blackhorse, I do see the same type of  generalization in the media

Not accurate for folks to  assume to judge one by the chemical make up of their preferred strains maybe, or maybe it will be?

 

I like high cbd plants, specifically thc>cbd. I dislike strains with cbd>thc

 

my leg is twisted and mangled from a 13 car pile up caused by a (the driver, not me) suicide attempt when I was 12. I wear out my left shoes in no time, dragging my club foot walk stance everywhere I go, untouched by multiple re breaks, a whole life of  leg, knee, foot braces, back braces, physical therapy, kinesiology, osteopathic manipulations, yoga, and a huge pile of chems they gave me until I was 18,  Luckily one shoulder and some ribs ended my 70 mph flight through the windshield. Many of my ribs were shattered in the assault. Constant pain is a part of my daily life, only because I refuse to take opiates, have surgery, or take anti depressants evidently.  I enjoy the physical relief as well as the mental relief when I use the strains I've come to choose in my garden. The side effects of my cannabis happen to be desired. I'd even partake to garnish them without remorse.

 

I suspect the thc assists in my well being as well as the cbd's. Weather one is for my head and the other my body, or maybe one is combined with the other to reward me with a ear perfect relief, I don't know.  

 

I will admit to this, which may be related to your post-

 

when I interview patients, and they indicate "I only want the highest thc strains", I move on. The patients that can power dab, joint after joint, bowl after bowl, are not within my comfort zone. I don't have a good time with power smokers, like I've seen at cannabis events. And when they don their favorite leaf costume, I'm out of there!   

 

The last thing I do with my cannabis is "party" .  

 

maybe people who smoke out of bongs are recreational users?

or ones who use that squeezy football hitter?

 sounds crazy to me, but that's just me.

 

peace blackhorse :)

Posted

GM: Most people (that use cbd) I know like to mix the cbd with regular smoke. One patient mixes it 50-50 and enjoys the pain relief. Another patient only uses high cbd trimmings to make cookies. Another only uses high thc for edibles.

 

I see a place for both strains in medical marijuana.

 

Sorry to hear of your accident when you were so young.

Posted

A 1:1 ratio is considered "CBD Rich" I'm assuming. Their study showed 1:1 and up to 15:1 cbd.

 

Like the reply's that people with PTSD are feeling better using the CBD Rich.

15 to 1 is in the CBD dominant realm.  There's hi CBD above 1%, CBD rich 1 to 1 and above and CBD dominant which I'm not sure the dividing line.  Those are the terms and definitions i've heard though.

Posted

Separating CBD from THC is like when Michael McDonald left the Doobie Brothers, they both suffered. 

Or it makes it easier to medicate.  I mix it in as need be.  if I'm feeling more anxious I start the day with a 50/50 mix and move to hi THC for the rest of the day.  Just decarbing alone makes a world of difference having your THC and CBD seperate.  This way you don't have to convert the attached THC to CBN when taking the longer time to decarb the CBD.  Works great for me.

Posted

Or it makes it easier to medicate.  I mix it in as need be.  if I'm feeling more anxious I start the day with a 50/50 mix and move to hi THC for the rest of the day.  Just decarbing alone makes a world of difference having your THC and CBD seperate.  This way you don't have to convert the attached THC to CBN when taking the longer time to decarb the CBD.  Works great for me.

I have different strains that I use to accomplish the same result. For example; OG Kush earlier in the day and Chem D later. I'm not so sure it's the ratio of THC to CBD that is the reason though. There are so many things going on with cannabis I feel that pinning the differences on one compound or another, or a ratio between the two, is just folly and a human tendency to over simplify something that's not all that simple. 

Posted (edited)

I doubt it is for you(THC to CBD ratio).  For me it's that simple since I've added HI amounts of CBD to get closer to a 50/50 ratio.  I can smoke any strain now and none get me paranoid at all.  

Such small differences in CBD content in teh strains you grow wouldn't have that much of a difference.  BUt the survey of patients listed above doesn't lie.  It states what ratios of THC and CBD those patients preferred.  All the other compounds obviously had a lesser degree of magnitude for the survey to show trends specifically with THC/CBD ratios.  or they somehow didn't differ in other cannabinoids, terpene and flavinoid levels.

Edited by Norby

Join the conversation

You can post now and register later. If you have an account, sign in now to post with your account.

Guest
Reply to this topic...

×   Pasted as rich text.   Paste as plain text instead

  Only 75 emoji are allowed.

×   Your link has been automatically embedded.   Display as a link instead

×   Your previous content has been restored.   Clear editor

×   You cannot paste images directly. Upload or insert images from URL.

Loading...
×
×
  • Create New...